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AIRR-C Membership Campaign

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On behalf of the AIRR Community Executive Sub-committee, we announce the AIRR Community Membership Campaign for 2020-2021. Current AIRR-C members are now considered “Legacy” members until they pay their annual dues. Please support the AIRR Community Membership Campaign today.

For further information about our ongoing initiatives, Working Groups, Sub-committees and membership benefits follow this link. AIRR Community Membership levels for 2020/2021 include:

  • AIRR-C Standard membership fee is $100 per year
  • AIRR-C Postdoc membership is free for up to 2 years
  • AIRR-C Student membership is free for up to 2 years

Thank you for paying your membership dues and for all that you do for the AIRR Community!

Nina Luning Prak, MD, PhD
AIRR Community Executive Sub-committee Chair

AIRR-C Software Working Group announces SONAR as the first certified AIRR compliant tool

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SONAR (v3) (Schramm et al. Front Immunol, 2016.) is the first tool certified as compliant with the AIRR-C v1.0 standard for AIRR-Seq software tools.

In an effort to enable rigorous and reproducible immune repertoire research at the largest scale possible, the AIRR-C Software Working Group has established a standard to validate software tools using the AIRR-C Standards and meeting a series of interoperability and quality criteria. Developers interested in certifying their tools should complete the checklist and submit it to the AIRR-C Software Working Group for evaluation and ratification by its members. 

More details can be found at the website AIRR Software WG – Guidance for AIRR Software Tools.

All compliant tools will be issued a badge and listed on the website AIRR Software WG – List of Tools Certified as Compliant.

 

AIRR Community Standards v1.3 and COVID-19 AIRR-Seq Data Available

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The AIRR Community, a grassroots group of immunologists, immunogeneticists and computer scientists who are dedicated to developing protocols and standards to facilitate sharing of these data is pleased to announce the release of v1.3 of the AIRR Standards, including v1.0 of the AIRR Data Commons API (ADC API) to query AIRR compliant data repositories. The AIRR Community also notes that the first repositories in the AIRR Data Commons, based completely on AIRR Standards, are now in production, with the iReceptor Public Archive and VDJServer repositories early adopters of these AIRR Standards. With the release of v3.0 of the iReceptor Scientific Gateway, it is possible for researchers to query the AIRR Data Commons, greatly expanding the ability of researchers to find and analyze AIRR-seq data in support of biomedical research and improving patient care.

The AIRR Community is also pleased to announce the availability of the first COVID-19 AIRR-seq data sets in the AIRR Data Commons. The COVID-19 data is from the Nielsen et al. paper and is currently stored in the community based AIRR COVID-19 repository and is searchable through the iReceptor Scientific Gateway (gateway.ireceptor.org). More studies from COVID-19 patients will be added in the coming weeks. The AIRR Community is tracking and curating COVID-19 AIRR-seq papers and data sets, including their availability in the AIRR Data Commons, on the b-t.cr web site (https://b-t.cr/t/publicly-available-covid-19-airr-seq-data-sets).

Finally, the Research Data Alliance recently released its “guidelines and recommendations on data sharing in the context of COVID-19“. AIRR Community members Brian Corrie and Christian Busse participated in the preparation of this document, and in particular the authoring of the section around recommendations for sharing COVID-19 AIRR-seq data.

Designated COVID-19 Section on the B-T.CR Forum

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Sharing is caring. This has become a key phrase during the COVID-19 pandemic. The AIRR Community proudly announces a designated channel in our data discussion forum B-T.CR (www.b-t.cr). This public resource will list all current and upcoming studies with immune repertoire data on COVID-19.

If you happen to stumble upon AIRR-seq or single cell RNA-seq data of COVID-19 research projects, please add them to the list found here!

COVID-19 Demands Increased Public Sharing of Biomedical Research Data

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Defeating the coronavirus pandemic will require unprecedented cooperation from the research community. This is especially true for the Adaptive Immune Receptor Repertoire Community (AIRR-C), given the paramount importance of antibodies and T cells for vaccines, diagnostics, and therapeutics in viral infection. Therefore, the AIRR-C hereby calls upon its members, and the wider research community, to share experiences, resources, samples, and data as openly and freely as possible, and to work within their respective systems to break down barriers to achieve this goal, subject to the overarching directives of respect, privacy, and protection for patients and all people. We are in this together.