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AIRR-C Software Working Group announces SONAR as the first certified AIRR compliant tool

June 23, 2020 by jpburckert

AIRR-C Software Working Group announces SONAR as the first certified AIRR compliant tool

SONAR (v3) (Schramm et al. Front Immunol, 2016.) is the first tool certified as compliant with the AIRR-C v1.0 standard for AIRR-Seq software tools.

In an effort to enable rigorous and reproducible immune repertoire research at the largest scale possible, the AIRR-C Software Working Group has established a standard to validate software tools using the AIRR-C Standards and meeting a series of interoperability and quality criteria. Developers interested in certifying their tools should complete the checklist and submit it to the AIRR-C Software Working Group for evaluation and ratification by its members. 

More details can be found at the website AIRR Software WG – Guidance for AIRR Software Tools.

All compliant tools will be issued a badge and listed on the website AIRR Software WG – List of Tools Certified as Compliant.

 

Filed Under: AIRR Community, New articles Tagged With: Adaptive Immune Receptor Repertoire Community

New AIRR-C Diagnostics Working Group initiated

January 18, 2020 by jpburckert

New AIRR-C Diagnostics Working Group initiated

The idea of a Diagnostics WG originated in May at the AIRR-C IV meeting in Genoa, Italy. The three initiators, Florian Rubelt (Roche Sequencing Solutions), Nicolas Schwab (UK Münster) and Christopher Gooley (Microsoft Research), felt that it was time for AIRR-based diagnostics to make their way into the clinic. The transition from an academic environment to a clinical setting creates new challenges, which will be of high interest within the AIRR Community and beyond. The AIRR-Community has a unique advantage to connect people from academia and industry from around the world and provides a great basis to identify and address these new challenges in the AIRR field. 

A group of interested participants held an ad hoc session at the Genoa meeting and at this point the AIRR-C Diagnostics Interim Working Group has held 9 calls with over 30 participants. Early discussions have revolved around identifying the set of tasks and the format of the group. 

A first agreed-upon product is a commentary about AIRR-based diagnostics. This initial commentary manuscript is meant to introduce AIRR-based diagnostics and the potential future opportunities to a clinical audience. The group has also ran a survey to identify the background and interests of the group. One outcome of the survey was to identify bottlenecks and challenges bringing AIRR based diagnostics to the clinic.

Currently, the AIRR-C Diagnostics interim working group is led by Florian Rubelt, Nicholas Schwab and Christopher Gooley and has more than 60 members.

For more information and updates please refer to the AIRR-C Diagnostics Interim Working Group website.

If you are interested in joining, please contact diagnostics@airrc.antibodysociety.org

Filed Under: AIRR Community, Meetings, New articles Tagged With: Adaptive Immune Receptor Repertoire Community, diagnostics, Meetings, working groups

Save the date for the next AIRR Community Meeting!

November 9, 2019 by jpburckert

We are excited to announce that AIRR Community Meeting V “Exploring New Frontiers” will be held in La Jolla, CA from December 8-12, 2020.

Meetings and presentations will take place at Scripps Research and the Hilton La Jolla Torrey Pines.

See AIRR C Meeting V Program at a Glance.

Filed Under: AIRR Community, New articles, Uncategorized Tagged With: Adaptive Immune Receptor Repertoire Community, Meetings

“Building Scientific Communities – Lessons Learned with AIRR”

November 1, 2019 by jpburckert

“Building Scientific Communities – Lessons Learned with AIRR”

AIRR-C Executive Sub-committee member Christian Busse gave a talk at the deRSE2019 (Konferenz für ForschungssoftwareentwicklerInnen in Deutschland – Conference for software engineers in Germany) on building scientific communities using the AIRR-C as an example.

Check out his talk here: https://doi.org/10.5446/42486.

Filed Under: AIRR Community, New articles Tagged With: Adaptive Immune Receptor Repertoire Community, Meetings, Presentations

Successful AIRR Community Meeting IV

October 15, 2019 by jpburckert

Successful AIRR Community Meeting IV

The fourth AIRR Community meeting (#AIRRC4) took place at the University of Genoa, May 11–15, 2019, in an unusual and gorgeous location. All talks were held in a 17th century church that has been repurposed for conference settings. The overarching theme of this meeting was “Bridging the Gaps” which aimed to address technological gaps between the amounts of accumulated data and our ability to process them, and the need for more involvement of stakeholder communities (industry, clinicians, patient communities) for the dissemination and implementation of the standards developed by the AIRR Community. 

AIRR Community meetings are the premier event for research on adaptive immune-receptor repertoires. They are also the primary location where the AIRR-Community’s Working Groups and Sub-committees come together in one location to discuss how to push standardization in AIRR-sequencing (AIRR-seq) data and analysis forward.  All meeting documents, slides, and video recordings can be found here:
https://www.antibodysociety.org/the-airr-community/meetings/communityiv/

Just like the biology of immune repertoires is high-dimensional, this meeting’s success was as well!  We gathered some of the numbers that best describe the success of the AIRR C IV meeting.

  • 2 Keynote speakers: Sai T. Reddy (ETH, Zürich, CH), Antonio Lanzavecchia (Instituto di Ricerca in Biomedicina, Bellinzona, CH)
  • 154 attendees from 5 continents and 22 countries
  • 18 invited speakers
  • 15 sponsors
  • This was the first time a twitter hashtag was used for an AIRR Community Meeting
  • Two pre-meeting workshops were held, teaching the basics of immunology, and of AIRR-seq data analysis 
  • AIRR-seq Tool demonstrations and Pipeline and Data Repository tutorial sessions were held

 

 

Filed Under: AIRR Community, New articles Tagged With: Adaptive Immune Receptor Repertoire Community, Meetings

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AIRR Community News

A newly certified AIRR-compliant software tool: The Immcantation Framework

A newly certified AIRR-compliant software tool: The Immcantation Framework

February 26, 2021 By jpburckert

The AIRR Community is excited to announce that the Immcantation Framework has been certified as compliant with the AIRR-C v1.0 standard for AIRR-Seq software tools. In an effort to enable rigorous and reproducible immune repertoire research at the largest scale possible, the AIRR-C Software Working Group has established a standard to validate software tools using the […]

Successful AIRR Community Meeting V

January 15, 2021 By Pam Borghardt

The fifth AIRR Community meeting (#AIRRC5) was held virtually Dec 8–10, 2020. The theme of this meeting was “Zooming in to the AIRR Community” connecting the global AIRR research community despite the pandemic for a series of Working Group & Sub-committee presentations, scientific sessions, interactive poster sessions, software tool demonstrations and networking events. AIRR Community […]

AIRR-C WG/SC Calls

All times are in ET (Americas/New York)

Click here for full calendar view

Call - ComRepo
10:00
Thu, March 4, 2021
Standards WG - Call
14:00
Mon, March 8, 2021
DST Anomaly
Sun, March 14, 2021
BioRes WG - Call
11:00
Wed, March 17, 2021
Exec SC
11:00
Thu, March 18, 2021

Recent AIRR Publications

  • Christley et al. “The ADC API: a web API for the programmatic query of the AIRR Data Commons” (Frontiers in Big Data, 2020)
  • Lees et al. “OGRDB: a reference database of inferred immune receptor genes” (Nucleic Acids Research, 2020).

 
See all publications

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