Texas A&M University Health Science Center
Department: Ibt – Cedp – Dashwood
Proposed Minimum Salary: Commensurate
Job Location: Houston, Texas
Job Type: Staff
The Research Associate will work in the Antibody and Biopharmaceutics Core (ABC) to develop new antibodies tailored to meet specific needs in disease prevention, treatment, and research applications. This individual will be responsible for screening and characterizing therapeutic antibodies and proteins using biochemistry, cell biology, and molecular biology techniques. The position has a strong emphasis on antibody engineering using in-silico modeling and phage display enabling the discovery of monoclonal antibodies, antibody libraries and fragments. The individual is expected to work in a highly collaborative environment within the Texas Medical Center, and demonstrate initiative and passion for solving difficult technical challenges.
Required Education and Experience: Appropriate bachelor’s degree. Two years of relevant experience. (Master’s degree is equivalent to two years of experience)
Required Knowledge, Skills, and Abilities:
Ability to multi-task and work cooperatively with others.
Ability to perform all tasks and job responsibilities safely without injury to self and others in compliance with A&M System and HSC guidelines.
Must be literate in the English language and able to comprehend and follow both written and verbal instructions.
Excellent interpersonal, oral and written communication skills in English.
Other Requirements or Other Factors: Occasional weekend and after hours work may be necessary.
Preferred Education and Experience:
Master’s degree or equivalent in biochemistry, biology or relevant field.
More than two (2) years of relevant clinical and/or laboratory experience.
Experience in molecular biology, including cloning and mutagenesis.
Familiarity with concepts of protein biochemistry and structural biology and computational skills for analysis of large datasets.
Preferred Knowledge, Skills, and Abilities: Proficient in antibody development techniques, such as hybridoma and phage display.
Select, design and perform protein biochemistry and structural biology techniques including: cloning and expression analysis, mutagenesis, and Polymerase chain reaction (PCR)
Perform antibody engineering using methods such as phage display, surface plasmon resonance, ELISA and related methods.
Collects, compiles, and records detailed data and reports them to the Principle Investigator.
Participate in weekly lab meetings within the center and participating program projects. Assist with the preparation of proposals for funding agencies, operation of research equipment, assist graduate students and other lab personnel. Performs other duties as assigned.
Special Note: A cover letter, resume, and contact information for three professional references are strongly recommended. You may upload all three on the application under CV/Resume.
Job posted: December 06, 2018
Join a Team that Lives to Improve Lives
People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what’s possible. And a focus on doing the day-to-day work that makes great science happen.
The following opportunity exists in our South San Francisco, CA headquarters:
Scientist/Sr. Scientist, Antibody Engineering, Genentech Research
We are seeking a talented Scientist/Senior Scientist to focus on antibody/protein engineering in the Genentech Research and Development (gRED) Department of Antibody Engineering.
The successful candidate will work with dynamic and highly motivated teams to drive the discovery and development of antibody therapeutics for unmet medical needs. The candidate will lead his/her own research lab and collaborate with diverse therapeutic areas, including cancer immunology, oncology, immunology and neuroscience. This position requires effective participation in multidisciplinary teams with members from Genentech Discovery Research, Developmental Sciences, and Pharma Technical Development. Primary responsibilities will include therapeutic antibody lead selection, optimization, format development, and engineering to support our internal antibody drug discovery programs and the advancement of lead molecules into the clinic.
The successful candidate is also expected to contribute to the research and development of new and cutting-edge antibody discovery technologies to enable first-in-class and best-in-class antibody therapeutics. This role will require creativity and forward-thinking approaches to develop technologies for Genentech’s future in antibody engineering by establishing a strong group by establishing productive collaborations across the organization.
Exceptionally strong leadership and communications skills are essential for the position, as this hire is expected to serve as a molecule or project team leader for various pipeline projects. Preferred individuals will embody passion for antibody and protein engineering through rational design and molecular evolution approaches.
Who You Are
The qualified individual will possess a Ph.D. in a biological science with at least 4 years of relevant experience in academia, biotechnology and/or pharma and possess a solid record of accomplishments and publications in a relevant scientific discipline.
The position requires a strong interest in protein engineering, structural biology, or biochemistry, drug discovery and development, as well as a deep commitment to working as part of teams to deliver breakthrough medicines.
Past experience in targeted or tissue-specific delivery is also valuable.
A Job with Benefits Beyond the Benefits
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
The next step is yours. To apply today, click here.
Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.
Job posted: November 21, 2018