Join a Team that Lives to Improve Lives
People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what’s possible. And a focus on doing the day-to-day work that makes great science happen.
The following opportunity exists in our South San Francisco, CA headquarters:
Scientist/Sr. Scientist, Antibody Engineering, Genentech Research
Description
We are seeking a talented Scientist/Senior Scientist to focus on antibody/protein engineering in the Genentech Research and Development (gRED) Department of Antibody Engineering.
The successful candidate will work with dynamic and highly motivated teams to drive the discovery and development of antibody therapeutics for unmet medical needs. The candidate will lead his/her own research lab and collaborate with diverse therapeutic areas, including cancer immunology, oncology, immunology and neuroscience. This position requires effective participation in multidisciplinary teams with members from Genentech Discovery Research, Developmental Sciences, and Pharma Technical Development. Primary responsibilities will include therapeutic antibody lead selection, optimization, format development, and engineering to support our internal antibody drug discovery programs and the advancement of lead molecules into the clinic.
The successful candidate is also expected to contribute to the research and development of new and cutting-edge antibody discovery technologies to enable first-in-class and best-in-class antibody therapeutics. This role will require creativity and forward-thinking approaches to develop technologies for Genentech’s future in antibody engineering by establishing a strong group by establishing productive collaborations across the organization.
Exceptionally strong leadership and communications skills are essential for the position, as this hire is expected to serve as a molecule or project team leader for various pipeline projects. Preferred individuals will embody passion for antibody and protein engineering through rational design and molecular evolution approaches.
For more information on Genentech’s gRED antibody engineering department, please see our Scientist profiles for Yan Wu and Paul Carter.
Who You Are
The qualified individual will possess a Ph.D. in a biological science with at least 4 years of relevant experience in academia, biotechnology and/or pharma and possess a solid record of accomplishments and publications in a relevant scientific discipline.
The position requires a strong interest in protein engineering, structural biology, or biochemistry, drug discovery and development, as well as a deep commitment to working as part of teams to deliver breakthrough medicines.
Past experience in targeted or tissue-specific delivery is also valuable.
A Job with Benefits Beyond the Benefits
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
The next step is yours. To apply today, click here.
Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.
At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.
Job posted: September 5, 2018
Senior Research Fellow
Molecular biologist/protein engineer
Faculty of Medicine
Centre for Cancer Immunology, University of Southampton
Salary range: £37,706 – 47,722 p.a.
The position will be held in the Centre for Cancer Immunology at Southampton General Hospital. This is a newly constructed, dedicated research building that is the result of a significant fund-raising campaign. It builds on a 40 year history of pioneering immunology and cancer research at Southampton, and represents the first dedicated cancer immunology centre in the UK. The activities in this centre span from pioneering discovery science to applied research and preclinical modelling and, crucially, onto first-in-human clinical trials and beyond. The centre houses world-class research facilities, including state-of-the-art scientific laboratories and a clinical trials unit.
The position is associated with the laboratory of Professors Ward and Ober who are relocating their research group from the USA to Southampton. Their interdisciplinary research program is dedicated to the development of novel antibody-based therapeutics that in the past has led to several therapeutics that are currently in advanced clinical trials. The group also develops advanced microscopy techniques for the evaluation of novel therapeutics in cellular environments. Their research is supported by major grants from the Wellcome Trust, Cancer Research UK and support from collaborating biopharma companies.
The appointee will be highly motivated and excited by the challenges involved in generating engineered antibodies for use in subcellular trafficking/microscopy studies and as therapeutics. The appointee is expected to have an outstanding background, including high quality publications, in using molecular biology approaches related to protein/antibody engineering, including experience in recombinant protein expression and characterisation. Experience in phage display, or other display techniques, is highly desirable. A proven track record of independently carrying out research is also a requirement.
Scientific knowledge in the areas described above equivalent to Ph.D. level with at least 2-3 years of additional experience is required. The post-holder will possess relevant academic qualifications and work experience as well as good IT skills. Non-UK/non-EU citizens are also welcome to apply.
To apply for the position, please click here. Informal enquiries should be directed to Professor E. Sally Ward (e.sally.ward@gmail.com) or Professor Raimund J. Ober (raimund.ober@gmail.com).
Job posted: August 21, 2018
Research Fellow
Molecular biologist/protein engineer
Faculty of Medicine
Centre for Cancer Immunology, University of Southampton
Salary range: £29,799-36,613 p.a.
The position will be held in the Centre for Cancer Immunology at Southampton General Hospital. This is a newly constructed, dedicated research building that is the result of a significant fund-raising campaign. It builds on a 40 year history of pioneering immunology and cancer research at Southampton, and represents the first dedicated cancer immunology centre in the UK. The activities in this centre span from pioneering discovery science to applied research and preclinical modelling and, crucially, onto first-in-human clinical trials and beyond. The centre houses world-class research facilities, including state-of-the-art scientific laboratories and a clinical trials unit.
The position is associated with the laboratory of Professors Ward and Ober who are relocating their research group from the USA to Southampton. Their interdisciplinary research program is dedicated to the development of novel antibody-based therapeutics that in the past has led to several therapeutics that are currently in advanced clinical trials. The group also develops advanced microscopy techniques for the evaluation of novel therapeutics in cellular environments. Their research is supported by major grants from the Wellcome Trust, Cancer Research UK and support from collaborating biopharma companies.
The appointee will be highly motivated and excited by the challenges involved in generating engineered antibodies for use in subcellular trafficking/microscopy studies and as therapeutics. The appointee is expected to have an outstanding background, including high quality publications, in using molecular biology approaches related to protein/antibody engineering, including experience in recombinant protein expression and characterisation. Experience in phage display, or other display techniques, is highly desirable.
Scientific knowledge in the areas described above equivalent to Ph.D. level is required. The post-holder will possess relevant academic qualifications and work experience as well as good IT skills. Non-UK/non-EU citizens are also welcome to apply.
To apply for the position, please click here. Informal enquiries should be directed to Professor E. Sally Ward (e.sally.ward@gmail.com) or Professor Raimund J. Ober (raimund.ober@gmail.com).
Job posted: August 21, 2018
