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You are here: Home / The AIRR Community / AIRR Community Working Groups / Standards Working Group

Standards Working Group

Purpose:

Develop a set of metadata standards (MiAIRR) for the submission of immune receptor repertoire sequencing datasets. Develop standardized file formats, schemas and data field names to represent MiAIRR metadata, annotated antibody and T cell receptor sequences, and any downstream data representations. These standards are defined in formal machine-readable specifications, allowing interoperability between software from different developers.

Goals:

Plans for 2021 include:

  • Finalize the current draft specifications for single-cell extensions (scXT) of the MiAIRR data standard
  • Prepare and publish a manuscript describing the revised MiAIRR 1.2 standard and the finalized scXT
  • Continue the “OntoVoc Team” in the current form as cross-WG activity to identify and recommend ontologies for AIRR Community standards
  • Clone, Tree, and Node objects defining clonal clustering, lineage trees, and individual tree nodes, respectively
  • Cell and Receptor objects defining individual cells and receptors, respectively
  • Manifest schema for packaging files together
  • Schema for grouping Repertoire objects
  • Redesign of data and sample processing schemas

Long term:

  • Community outreach and schema adoption
  • Refine existing standards, tools, and documentation
  • Enable other working groups
  • Develop new standards

Members:

Co-leaders: Christian Busse, Scott Christley and Jason Vander Heiden

Members: TBA

Contact: TBA

Resources:

Visit the Data Representation Working Group Projecon the B-T.CR Wiki.

Visit the Data Representation Working Group Project on GitHub.

Visit the AIRR Standards Documentation.

Contact: standards@airrc.antibodysociety.org

 

AIRR Community News

AIRR Community Merchandise Shop Now Open!

April 28, 2022 By Pam Borghardt

The AIRR Communications Sub-committee is pleased to announce the launch of an online merchandise shop featuring AIRR Community logo’d merchandise. Shirts, hoodies, tote bags and stickers are currently available, with additional designs to be added in the future. Be sure to check out the special Immuno-Collection while you are browsing! All products are constructed from certified […]

AIRR Community 2022 Executive Sub-committee Election

April 4, 2022 By Pam Borghardt

With each major meeting interval of the AIRR Community, elections are held for leadership positions on the AIRR-C Executive Sub-committee.  This spring, per our governance, we are seeking nominations for Executive SC Chair-Elect and up to three members of the Executive SC. To nominate an individual to serve on the AIRR-C Executive SC, the nominator […]

AIRR-C WG/SC Calls

All times are in ET (Americas/New York)

Click here for full calendar view

Call - Software
11:30
Wed, July 6, 2022
Call - Legal & Ethics
12:00
Mon, July 11, 2022
Call - Standards
14:00
Mon, July 11, 2022
Call - GLDB WG (Western Hemisphere)
12:00
Tue, July 19, 2022
Call - GLDB WG (Eastern Hemisphere)
10:00
Wed, July 20, 2022

Recent AIRR Publications

  • Trück J et al, Biological controls for standardization and interpretation of adaptive immune receptor repertoire profiling (eLife, 2021)
  • Arnaout RA, Prak ETL, Schwab N, Rubelt F. Adaptive Immune Receptor Repertoire Community. The Future of Blood Testing Is the Immunome. (Frontiers in Immunology, 2021).

 
See all publications

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