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You are here: Home / The AIRR Community / AIRR Community Working Groups / Software Working Group

Software Working Group

Purpose:

To make it easy to do rigorous analysis of AIRR-seq data.

Achievements:

We have defined a standard for AIRR-Seq software tools. We will promote this over the next year, as a way of encouraging inter-operation and adoption of AIRR standard protocols by providing community support and publicity to compliant tools. We have also started work (in collaboration with the Germline Database Working Group) on an initiative to assess the biological credibility of an AIRR-Seq repertoire, and to identify common technical errors that can occur during its preparation, which can be heard to spot from read quality annotations and other technical measures commonly available today.

Goals:

Plans for 2022/23 include:

  • Completion of RepCred
  • Alignment of benchmarking and gold-standards dataset with PrecisionFDA activities
  • Surveying our AIRR-C membership for key focus areas (particular emphasis on industry needs)
  • Supporting the Communications SC industry initiative by drawing on members’ knowledge of the tools marketplace

Long-term vision and how WG products integrate with the AIRR-C mission:

The purpose of our working group is to encourage practices that enable software tools to work, and to work with one another: this dovetails with the AIRR-C mission to improve methods and standards. We aim to promote awareness of AIRR standards within the software tools community, and to provide a forum through which software tools developers can discuss and progress topics of mutual interest.

Members:

Co-Leaders: William Lees and Chaim Schramm

Members: Bryan Briney, Brian Corrie, Noah Yann Lee, Georgina Leslie, William Lees (Co-lead) Susanna Marquez, Luke Myers, Mats Ohlin, Chaim Schramm (Co-lead), Adrian Shepherd, and Wenming Xiao.

Resources:

  • Compliance Checklist for AIRR Software Tools
  • AIRR Software WG – List of Tools Certified as Compliant
  • Gold standard datasets

Contact: software@airr-community.org

AIRR Community News

TRUST4 is now certified as AIRR-compliant

March 1, 2023 By Edel Aron

The AIRR Community is excited to announce that TRUST4 has been certified as compliant with the AIRR-C v1.0 standard for AIRR-Seq software tools. TRUST4 (Tcr Receptor Utilities for Solid Tissue 4) is a tool for assembling BCRs and TCRs from bulk and single-cell RNA-Seq data. In an effort to enable rigorous and reproducible immune repertoire […]

AIRR Data Commons and iReceptor Science Gateway Start Major Collaboration with Type-1 Diabetes Researchers

January 11, 2023 By Pam Borghardt

The AIRR Community is pleased to announce the addition of a new Type 1 Diabetes (T1D) focused repository in the AIRR Data Commons. This is a collaboration between the iReceptor team (Simon Fraser University), The Sugar Science group, the Aaron Michels Lab (University of Colorado), and the Todd Brusko Lab (University of Florida) among others. This repository contains the first fully HLA/MHC […]

AIRR-C WG/SC Calls

All times are in ET (Americas/New York)

Click here for full calendar view

DST Anomaly
Sun, March 12, 2023
Common Repository WG
11:00
Thu, April 6, 2023
Diagnostics WG
11:00
Tue, April 11, 2023
Standards WG
14:00
Mon, April 17, 2023
Call - GLDB WG (Eastern Hemisphere)
4:00
Wed, April 19, 2023

Recent AIRR Publications

Lees W.D. et al. AIRR Community curation and standardised representation for immunoglobulin and T cell receptor germline sets (Immunoinformatics, 2023)

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