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You are here: Home / AIRR Community / AIRR Community and PrecisionFDA COVID-19 Precision Immunology App-a-thon

AIRR Community and PrecisionFDA COVID-19 Precision Immunology App-a-thon

December 28, 2020 by Pam Borghardt

The AIRR Community is helping to lead the PrecisionFDA COVID-19 Precision Immunology App-a-thon.  

This is part of the “precisionFDA Challenges” program, which is designed to engage and improve software that analyzes NGS (next generation sequencing data) through community challenges. There were 68 bioinformaticians pre-registered for the Precision Immunology Challenge, and more are expected to join as the app-a-thon continues.  These “citizen scientists” will form teams to design software that will make AIRR-seq data more available and accessible for immunologists to realize the promise of immunological big data for improved diagnostics and therapeutics in immunotherapy.

The Precision Immunology Challenge uses AIRR-seq repertoire data from COVID-19 patients downloaded from the AIRR Data Commons (VDJServer and iReceptor Public Archive) through the iReceptor Gateway. These data sets have been carefully chosen to include data on patient demography and clinical outcome in order to illuminate the relationship between personalized adaptive immunity molecular data and COVID-19 disease variables.

The AIRR Community Diagnostics Working Group published a blog post as part of this effort, explaining the possible uses of AIRR-seq data in the clinic in the near future.

The app-a-thon runs through February 2021 at which time the apps will be judged for usability, impact and innovation.

 

Filed Under: AIRR Community, COVID-19, Food and Drug Administration

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AIRR Community News

Successful AIRR Community Meeting V

January 15, 2021 By Pam Borghardt

The fifth AIRR Community meeting (#AIRRC5) was held virtually Dec 8–10, 2020. The theme of this meeting was “Zooming in to the AIRR Community” connecting the global AIRR research community despite the pandemic for a series of Working Group & Sub-committee presentations, scientific sessions, interactive poster sessions, software tool demonstrations and networking events. AIRR Community […]

AIRR Community and PrecisionFDA COVID-19 Precision Immunology App-a-thon

December 28, 2020 By Pam Borghardt

The AIRR Community is helping to lead the PrecisionFDA COVID-19 Precision Immunology App-a-thon.   This is part of the “precisionFDA Challenges” program, which is designed to engage and improve software that analyzes NGS (next generation sequencing data) through community challenges. There were 68 bioinformaticians pre-registered for the Precision Immunology Challenge, and more are expected to join […]

AIRR-C WG/SC Calls

All times are in ET (Americas/New York)

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ComRepo WG - Call
10:00
Thu, January 28, 2021
Meetings SC
10:30
Tue, February 2, 2021
BioRes WG - Call
10:00
Wed, February 3, 2021
Standards WG - Call
14:00
Mon, February 8, 2021
Exec SC w. Co-leads
11:00
Tue, February 16, 2021

Recent AIRR Publications

  • Christley et al. “The ADC API: a web API for the programmatic query of the AIRR Data Commons” (Frontiers in Big Data, 2020)
  • Lees et al. “OGRDB: a reference database of inferred immune receptor genes” (Nucleic Acids Research, 2020).

 
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