The AIRR-C Diagnostics Working Group recently published a manuscript on using the immunome for blood testing in Frontiers in Immunology. In the manuscript, the AIRR-C discusses opportunities as well as the current state of immunome-based diagnostics and highlights some of the challenges involved. The authors conclude with a call to clinicians, researchers, and others to join efforts AIRR-C to realize the diagnostic potential of the immunome. In the paper, the researchers define immunome as “millions of V(D)J-rearranged antibody and T cell receptor genes collectively expressed by a person’s B cells (antibodies) and T cells”.
The Future of Blood Testing Is the Immunome. (Frontiers in Immunology, 2021).
Arnaout RA, Prak ETL, Schwab N, Rubelt F. Adaptive Immune Receptor Repertoire Community.