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You are here: Home / Archives for Adaptive Immune Receptor Repertoire Community

Join us for the next AIRR-C webinar on Nov 7th!

October 31, 2023 by Edel Aron

Drs. Encarnita Mariotti-Ferrandiz and Nina Luning Prak, members of the Adaptive Immune Receptor Repertoire (AIRR) Community Biological Resources Working Group, will describe quality control (QC) procedures for immune repertoire profiling. Dr. Mariotti-Ferrandiz will describe QC pipelines for sequencing of T cell receptor gene rearrangements that are in use in her laboratory in the Department of Immunology, Immunopathology and Immunotherapy at the Sorbonne. Next, Dr. Luning Prak will describe QC pipelines for sequencing of B cell receptor gene rearrangements that are in use in her laboratory and in the Human Immunology Core facility at the University of Pennsylvania. They will then focus on frequently asked questions and respond to other questions posed by attendees during a Q&A period.

Registration is open. Visit the AIRR Community Webinar Series website to learn more about this series, and access the recordings of past sessions.

Filed Under: AIRR Community Tagged With: Adaptive Immune Receptor Repertoire Community

Reconnect with the AIRR Data Commons: Your Gateway to Immunology Discoveries

September 19, 2023 by Edel Aron

The AIRR Community continues to spearhead innovation in immunology research with the ever-expanding AIRR Data Commons (ADC). For those unfamiliar, the ADC is a pioneering initiative that enables the sharing of standardized Adaptive Immune Receptor Repertoire (AIRR) data. This resource hosts a wealth of information about the diverse array of antibody/B-cell and T-cell receptors that govern immune responses, obtained from bulk and single-cell sequencing technologies. By facilitating the exchange of this valuable data, the ADC enables researchers to gain deeper insights into immunity, disease progression, and therapeutic interventions.

From its inception in 2018 with under 400 million sequence annotations, the ADC has expanded into nine distributed repositories housing 89 studies, over 9800 sample repertoires, and an astonishing 5.2 billion sequence annotations. But this growth is not just about numbers – it’s about fostering collaboration and igniting discoveries. Scientists around the world can access a unified platform to discover, compare, and analyze immunological data, transcending the limitations of individual labs. This interconnectedness not only drives innovation but also eliminates redundancy, saving precious time and resources.

As we look to the future, the ADC is poised to play an even more pivotal role. Its flexible, collaborative framework and continued growth in data will likely attract interdisciplinary partnerships that foster a holistic understanding of the immune system’s complexities. Moreover, the integration of technologies such as machine learning and AI promise to extract deeper insights from the wealth of data, unraveling intricate mechanisms of the immune response.

The AIRR Community’s effort to build and maintain the ADC transcends geographical boundaries and institutional affiliations, exemplifying the spirit of scientific inquiry. As we celebrate the achievements thus far, we eagerly anticipate the advancements that this collaborative endeavor will bring to immunology research in the years to come.

The ADC can be searched interactively using a web user interface at the iReceptor Gateway or VDJServer Community Data Portal. To contribute to the ADC, consider setting up a local repository via the iReceptor Turnkey or submitting data through the VDJServer Community Data Portal.

Filed Under: ADC, AIRR Community Tagged With: Adaptive Immune Receptor Repertoire Community

September Seminar Series

September 12, 2023 by Edel Aron

The September AIRR-C seminar is fast approaching! On September 28th at 7:00 PST/10:00 EST/16:00 CET, Pieter Meysman of the University of Antwerp will be discussing the applications of TCR-epitope prediction models and Felix Drost of Helmholtz Munich will be discussing the prediction of T cell receptor functionality against mutant epitopes.

Register now! The seminar will last approximately 90 minutes.

Filed Under: AIRR Community Tagged With: Adaptive Immune Receptor Repertoire Community, Seminar, T cells

On AIRR Podcast Episode 14 Now Available!

August 8, 2023 by Edel Aron

In the latest episode of the On AIRR – An AIRR-C Podcast Series, Dr. Ulrik Stervbo and Dr. Zhaoqing Ding speak with Alexander Bernier BCL, JD, LLM, a lawyer with expertise in biological data sharing designs, about data protection and data sharing. We discuss the risk of identifying individuals in a biological data set, how this is approached differently in different countries, and possible strategies to ensure data privacy.

You can subscribe and listen in your favorite podcasting app or check out all of the On AIRR episodes here at http://onairr.airr-community.org or on the AIRR YT Channel. If you share podcast-related content in social media, please remember to use the hashtag #onairr!

 

Filed Under: AIRR Community Tagged With: Adaptive Immune Receptor Repertoire Community, podcast

Mastodon

July 20, 2023 by Edel Aron

Exciting news from the AIRR Community! We have expanded our social media presence to Mastodon.

This innovative, decentralized platform aligns with our commitment to open scientific collaboration, allowing us to reach a broader audience. From now on, you can find our latest updates, discussions, and breakthroughs in the field of Adaptive Immune Receptor Repertoire research on Mastodon.

We invite you to follow us on Mastodon, join our conversations, and stay informed about the latest AIRR topics. Our commitment remains to drive innovation, enhance scientific discourse, and share science openly and freely with everyone interested.

Join us on Mastodon: https://fediscience.org/@airr_community

#OpenScience #Immunology #AIRR #DecentralizedSocialMedia

Filed Under: AIRR Community Tagged With: Adaptive Immune Receptor Repertoire Community, Social

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AIRR Community News

Join Tabs and the AIRR-C for the First TAbS Townhall!

October 2, 2025 By Lorissa Corrie

TAbS is excited to welcome you to the very first Townhall Meeting on October 15, 2025! 🎉 Join the event on Zoom using this LINK as they share the latest updates about the organization, highlight new and ongoing programs, and introduce the committees and resources available to members. This will also be a great opportunity […]

Episode 19 of the On AIRR podcast is here! What does it take to prepare for the next pandemic?

September 14, 2025 By Lorissa Corrie

In this episode, we explore ReVAMPP (Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness), an NIH-funded initiative focused on pathogens that pose significant public health risks, including emerging viruses with pandemic potential. Together with Dr. Lauren Williamson and Dr. Robert Carnahan (Vanderbilt University Medical Center) and Dr. Matthew Vogt (University of North […]

AIRR Community WG Calls

All times are in ET (Americas/New York)

Click here for full calendar view

Call - Comms & Meetings SC
12:00
Fri, October 17, 2025
DST Anomaly
Sun, October 26, 2025
Call - ComRepo WG
11:00
Thu, November 6, 2025
Call - Standards WG
12:00
Thu, November 13, 2025
AIRR Community Seminar Series
10:00
Thu, November 20, 2025

Recent AIRR Publications

Lees W.D. et al. AIRR Community curation and standardised representation for immunoglobulin and T cell receptor germline sets (Immunoinformatics, 2023)

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