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You are here: Home / Archives for Adaptive immune receptor repertoire

AIRR-C Extended Deadline – Special Issue in Immunoinformatics

February 17, 2025 by Pam Borghardt

Attention Researchers!

Great news! The submission deadline for the AIRR-C Special Issue in Immunoinformatics has been extended to April 15, 2025.

This is a unique opportunity to showcase your work—whether it’s original research, reviews, tutorials, tools, or commentaries—and contribute to a landmark publication highlighting the innovation and impact of the AIRR field.

Don’t miss the chance to share your insights and be part of this special issue!

We look forward to your submissions.

Filed Under: Adaptive immune receptor repertoire

Announcing the AIRR Community Seminar Series!

April 6, 2023 by Pam Borghardt

Join the AIRR Community for a 90 minute “lab-style” virtual seminar.  Each month an established and an early career scientist will discuss their AIRR-seq related research. Seminar time will be 16:00 – 17:30 Central European Time (CET), typically on the 4th Thursday of the month.  Most talks will be recorded and posted on the AIRR Community YouTube channel.  In the spirit of open science collaboration we want to give credit where credit is due – this seminar series is modelled after and a follow-up to the highly successful iReceptor Plus Seminar Series: Theories and Applications of Immune Repertoires which ran from 2020-2022. Check out their website for many scientifically related talks!

Register today for the April 27th talks presented by Hashem Koohy from Oxford University and Marcos Vieria from University of Chicago.

Check out the seminar series web page for upcoming seminars and registration links.

 

Filed Under: Adaptive immune receptor repertoire, AIRR Community

AIRR Data Commons and iReceptor Science Gateway Start Major Collaboration with Type-1 Diabetes Researchers

January 11, 2023 by Pam Borghardt

The AIRR Community is pleased to announce the addition of a new Type 1 Diabetes (T1D) focused repository in the AIRR Data Commons. This is a collaboration between the iReceptor team (Simon Fraser University), The Sugar Science group, the Aaron Michels Lab (University of Colorado), and the Todd Brusko Lab (University of Florida) among others. This repository contains the first fully HLA/MHC genotyped study that adheres to the the AIRR v1.4 MHC genotype standard, with over 62 million annotated sequences from 359 repertoires from the Mitchell et al. longitudinal study of TCR repertoires (TRB locus) in children who progressed to T1D. This new T1D AIRR-seq data is searchable through the iReceptor Gateway and there is of course more T1D data to come from this collaboration. We encourage the community to share this valuable type of data!

Filed Under: Adaptive immune receptor repertoire, AIRR Community

AIRR Community Standards v1.4 Now Available

September 19, 2022 by Pam Borghardt

The AIRR Community is pleased to announce the release of v1.4 of the AIRR Standards, including v1.2 of the AIRR Data Commons API (ADC API) to query AIRR compliant data repositories. This release enables additional compatibility with single-cell and emerging technologies, supports extended data/metadata capture, and improves data standardization and integration. Major changes include updated quantification fields and conversion of several fields to ontology references to provide consistency across studies.

Several exciting experimental releases are included in this update: new Germline and Genotype schemas for documenting VDJ germline reference sequences and subject VDJ and MHC genotypes, extensions to the Cell schema for storing single-cell gene expression and receptor reactivity, and data aggregation schemas to facilitate more complex and reproducible analyses.

The ADC API specification included in this release contains new capabilities for querying AIRR v1.4 Schema objects including Clone, Cell, CellExpression, and Receptor objects.

Check out these key links:

Python Package

R Package

Release Notes

Github

Filed Under: Adaptive immune receptor repertoire, AIRR Community Tagged With: Adaptive Immune Receptor Repertoire Community

Announcing the inaugural AIRR Community Service Prize Winner!

July 8, 2022 by Pam Borghardt

We are thrilled to announce the inaugural AIRR Community Service Award winner, which recognizes individuals who have made significant contributions to the AIRR Community. The first recipient of this award was Dr. Christian Busse, a distinguished immunologist and pioneer in the field of AIRR research who was presented with the award at the AIRR Community Meeting VI in La Jolla, California in May 2022. 

The AIRR Community Service Award was established to acknowledge individuals who have demonstrated a deep commitment to the AIRR Community, including contributions to the development of standards and tools for the analysis of immune receptor repertoires, advancing the field through research, and sharing knowledge with other members of the community.

Christian Busse, of DKFZ in Germany, has been an active member of the AIRR Community for many years, serving as a member of the Executive Sub-committee and Co-lead of the Standards Working Group. In these roles he contributes to the development of standards and best practices for AIRR analysis, helping to ensure that the Community continues to advance and grow.

We would like to extend our warmest congratulations to Christian Busse on this well-deserved award. His contributions to the AIRR Community have been truly outstanding, and we are honored to recognize him as the first recipient of the AIRR Community Service Award!

Filed Under: Adaptive immune receptor repertoire, AIRR Community, AIRR Community Service Prize

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AIRR Community News

Zooming into the Community III Starts Tomorrow!

May 20, 2025 By Lorissa Corrie

Join us tomorrow for our 10th Anniversary AIRR-C online event! 📢 This virtual two-day meeting marks the 10th anniversary of the founding of the AIRR Community. Join us for a celebration of the AIRR Community and two scientific sessions on “Specificity.” ⚠️ Service announcement: Each registration day is independent, with its own unique Zoom link! […]

New episode of the On AIRR podcast is here!

March 25, 2025 By Lorissa Corrie

In this episode of On AIRR, we welcome Dr. Bjoern Peters, Professor at the La Jolla Institute for Immunology, to discuss the crucial role of high-quality data in AI-driven immunological predictions and diagnostics. Dr. Peters shares his journey from theoretical physics to MHC-binding prediction, leading to his work on the Immune Epitope Database (IEDB) — […]

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The Adaptive Immune Receptor Repertoire Community is a research-driven group organizing around the use of high-throughput sequencing technologies to study antibody/B-cell and T-cell receptor repertoires.

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