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You are here: Home / The AIRR Community / AIRR Community Meetings / AIRR Community Meeting IV: “Bridging the Gaps” / AIRR Community Meeting IV: Recorded Talks

AIRR Community Meeting IV: Recorded Talks

May 11-15, 2019, University of Genoa, Italy

Follow us on Twitter: #AIRRC4

Welcome to the AIRR Community Meeting IV Video Portal. Below, you can find recordings of all our session talks.

Switch to our members-only section to download the slides!

Day 1

Workshop II: Jamie K Scott (Simon Fraser University, CA) — “Fundamentals of the Immune System” — No video available for this talk
Workshop II: Victor Greiff (University of Oslo, NO) — “Steps in AIRR data processing and Analysis: best practices, pitfalls and future directions” — No video available for this talk
Panel Discussion: Germline Databases (GLDB) WG —  “Beyond inferred alleles: Improving the quality, scope and openness of GLDBs through software inference, open publication and population-level data” — Video

Day 2

Panel Discussion: Common Repositories, Data Representation and Minimal Standards WGs —
“Towards Solutions: The Benefits and Challenges of Sharing AIRR-seq Data” — Video

Day 3

Keynote: Sai Reddy (ETH Zurich, CH): “Integration of systems immunology and immune repertoires” — Video

Scientific Session I: Advances in Understanding Biological Processes of the AIRR

Talk 1: Nicholas Schwab (University of Muenster, DE): “Sex bias in MHC I-associated shaping of the adaptive immune system” — Video
Talk 2: Lindsay Cowell (University of Texas, Southwestern Medical Center, US): “Statistical classifiers for detecting phenotype-associated biophysicochemical motifs in AIRR” — Video
Talk 3: David Klatzmann (Sorbonne Universite, FR): “How specific is specific (in the T-cell response)?” — Video
Talk 4: Tom Parks (University of Oxford, UK): “Germline immunoglobulin heavy-chain locus variation and susceptibility to group A streptococcal disease” — Video

Poster Talks

Short Talk 1: Kenneth Hoehn (Yale University, US): ”Repertoire-wide phylogenetic models of B-cell molecular evolution reveal evolutionary signatures of aging and vaccination” — Video
Short Talk 2: Ivana Mikocziova (University of Oslo, NO): “AIRR-seq reveals a large number of germline polymorphisms in the variable immunoglobulin genes” — No video available for this talk
Short Talk 3: Pieter Meysman (University of Antwerp, BE): “On the viability of unsupervised T-cell receptor sequence clustering for epitope preference” — Video

Challenge Session I: Challenges in Processing and Storing Massive AIRR-seq Data (>1bn sequences)

Talk 1 – Processing & Annotation: Mikhail Shugay (Skolkovo Institute of Science and Technology, CZ): “Challenges in motif discovery and comparative analysis of large T-cell receptor repertoire datasets” — Video
Talk 2 – Analysis: Bryan Briney (Scripps Research, US): “Commonality despite exceptional diversity in the baseline human antibody repertoire” — Video
Talk 3 – Data Storage & Access: Xiao Liu (BGI Shenzhen, CN): “Pan Immunome Initiative and applications in health and disease” — Video

Day 4

Keynote: Antonio Lanzavecchia (Institute for Research in Biomedicine, CH): “Lessons from the analysis of the immune response to P. falciparum: The power of clonal selection” — No video available for this talk

Scientific Session II:  Advances in AIRR-seq Data Addressing Human Health and Disease

Introduction: Steve Kleinstein (Yale School of Medicine, US) on sharing AIRR-seq data — Video

Talk 1: Rachael Bashford-Rogers (University of Oxford, UK): “Mapping B-cell receptor repertoires in immune-mediated diseases” — Video
Talk 2: Rob Holt (BC Cancer Research Centre, UBC/SFU, CA): “Mining the tumor-associated T cell repertoire for TCR therapeutics” — Video
Talk 3: Olga Britanova (Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, RU): “Potential use of monoclonal anti-TCR antibody for treatment of autoimmune diseases.” — Video
Talk 4: Ziv Shulman (The Weizmann Institute of Science, IL): “Dynamics of B cell immune responses in intestinal tissues” — Video

Poster Talks

Short Talk 1: Felix Breden (Simon Fraser University, CA): “iReceptor Plus facilitates sharing and analysis of AIRR-seq data” — Video
Short Talk 2: Xihao Hu (Dana Farber Cancer Institute, US): “Landscape of B-cell immunity and related immune evasion in human cancers” — Video
Short Talk 3: Keshav Motwani (University of Florida, US): “T-cell receptor repertoires in peripheral blood encode type-1 diabetes status” — Video

Patient and Community Engagement

Talk 1: Tania Bubela (Simon Fraser University, CA): “A primer on patient-oriented research” — Video
Talk 2: Harriet Teare (University of Oxford, UK): “Dynamic consent: Individual oversight and control of data and samples” — Video
Talk 3: Namaste Marsden (BC First Nations Health Authority, CA): “We are relational: The challenge of Indigenous collective rights in bio-ethics” — Video
Panel Discussion: Patient & Community Engagement — Video

Engaging Industry

Talk 1: Jacob Glanville (Distributed Bio, US): “Applied repertoire analysis – Computational immunoengineering of therapeutic antibodies and TCRs” — Video
Talk 2: Jonathan Carlson (Microsoft Research, US): “The Adaptive-Microsoft TCR-Antigen Map Project” — No video available for this talk
Talk 3: Nicola Bonzanni (Enpicom, NE): “Bridging the gap: Manage, analyze, visualize and interpret repertoire sequencing data using the IGX platform” — Video

 

Click here to return to the meeting site.

AIRR Community News

Zooming into the Community III Starts Tomorrow!

May 20, 2025 By Lorissa Corrie

Join us tomorrow for our 10th Anniversary AIRR-C online event! 📢 This virtual two-day meeting marks the 10th anniversary of the founding of the AIRR Community. Join us for a celebration of the AIRR Community and two scientific sessions on “Specificity.” ⚠️ Service announcement: Each registration day is independent, with its own unique Zoom link! […]

New episode of the On AIRR podcast is here!

March 25, 2025 By Lorissa Corrie

In this episode of On AIRR, we welcome Dr. Bjoern Peters, Professor at the La Jolla Institute for Immunology, to discuss the crucial role of high-quality data in AI-driven immunological predictions and diagnostics. Dr. Peters shares his journey from theoretical physics to MHC-binding prediction, leading to his work on the Immune Epitope Database (IEDB) — […]

AIRR Community WG Calls

All times are in ET (Americas/New York)

Click here for full calendar view

Webinar - Zooming into the AIRR Community III
11:00
Wed, May 21, 2025
Webinar - Zooming into the AIRR Community III
11:00
Thu, May 22, 2025
Call - ComRepo WG
11:00
Thu, June 5, 2025
Call - Standards WG
12:00
Thu, June 12, 2025
Call - Standards WG
14:00
Mon, June 16, 2025

Recent AIRR Publications

Lees W.D. et al. AIRR Community curation and standardised representation for immunoglobulin and T cell receptor germline sets (Immunoinformatics, 2023)

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