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You are here: Home / Archives for Adaptive immune receptor repertoire

Needs and challenges of biological controls for AIRR-sequencing standardization: an AIRR-C review published in eLife

July 31, 2021 by Pam Borghardt

Announcing the latest AIRR Community publication!

Adaptive Immune Receptor Repertoire (AIRR) can be deeply analyzed to study its complexity thanks to AIRR-sequencing (AIRR-seq) based on high throughput sequencing. However, like many high-throughput technologies, AIRR-seq comes with several technical challenges, notably the lack of established controls and standards, a necessity when considering current available and envisioned AIRR-seq applications. The Biological Resources Working Group within the AIRR Community, established in 2017, aims at studying, prioritizing and developing biological controls and standardization reagents for AIRR-seq studies. In this article, they review current practices, resources and considerations for using and developing AIRR-seq standards and controls.

Filed Under: Adaptive immune receptor repertoire, AIRR Community, Biological controls Tagged With: Adaptive Immune Receptor Repertoire Community

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